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Isayev Lab
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  1. Research

Research

Our research focuses on developing and applying machine learning methods to solve challenging problems in computational chemistry and materials science.

Machine Learning Potentials

Machine Learning Potentials

Transferable neural network potentials bridging quantum accuracy with computational efficiency for molecular simulations

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AI for Drug Discovery

AI for Drug Discovery

Energy-driven, decision-oriented computational methods integrating machine learning for pharmaceutical applications

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Generative AI in Chemistry

Generative AI in Chemistry

Generative models enabling systematic exploration of chemical space under biological and synthetic constraints

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Experiment Automation

Experiment Automation

ML-enabled workflows for scalable, reliable, and reproducible chemical experimentation in cloud laboratories

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Quantum Chemistry

Quantum Chemistry

First-principles electronic structure methods providing the theoretical foundation for ML potential development

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Materials Informatics

Materials Informatics

Machine learning-accelerated discovery and optimization of advanced functional materials

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Reactions & Reactivity

Reactions & Reactivity

ML-accelerated reaction modeling enabling exploration of chemical transformations at unprecedented scale

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Our Approach

We believe in combining rigorous theoretical foundations with practical applications. Our work bridges the gap between fundamental science and real-world impact, always with an eye toward reproducibility and open science.

Isayev Lab

Department of Chemistry

Carnegie Mellon University

Pittsburgh, PA 15213

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Contact

Email: oisayev@andrew.cmu.edu

Office: Mellon Institute

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